Event Host: Ohio State Libraries
Short Description: Although our immune system is quite good in protecting us from being eaten by most of microorganisms, some of them are quite efficient in breaking this barrier. On both sides, fighting strategies involve pressing on "weak spots" for making "strong points". Some of those recently discovered in our laboratory will be discussed during this meeting.
Too small to be seen by naked eye, microorganisms certainly deserve to be noticed and studied due to the enormously important roles, both beneficial and detrimental, they play in our lives. Having more than 10 times bacterial than human cells in and on our bodies, how do we manage to survive in this kingdom of tiny beasts thirsty for food? Although our immune system is quite good in protecting us from being eaten by most of microorganisms, some of them are quite efficient in breaking this barrier. On both sides, fighting strategies involve pressing on "weak spots" for making "strong points". Some of those recently discovered in our laboratory will be discussed during this meeting.
About the Speaker:
Dmitri Kudryashov, assistant professor, chemistry and biochemistry, was born in Soviet Union and obtained his education in Russia. He moved to the United States in 2001 for postdoc at UCLA with Prof. Emil Reisler to study the actin cytoskeleton. At that time he got involved in deciphering pathogenic mechanisms of Actin Crosslinking Domain (ACD) - one of the toxins produced by V.cholerae that disrupts the host immune response by neutralizing actin.
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